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In summary, this study demonstrates that calcium overload plays a critical role in the cytotoxicity associated with a-synucleinopathy, leading to mitochondrial damage, lysosomal dysfunction, and cell death

A Therapeutic Use Exemption (TUE) allows a WADA-tested athlete to use a prohibited substance for a legitimate medical need

Lancet 399, 473486

18 , 19 , 20 Furthermore, a high expression of STAT3 alters the cell cycle 21 , 22 and inhibits the apoptosis by upregulating anti-apoptotic signaling 23 , 24 in inflammation-associated CRC and other human cancers